What allergy medicine is safe to take while breastfeeding

Cetirizine use while Breastfeeding

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Medically reviewed by Final updated on Apr 22,


Cetirizine Identification

Substance Name

Cetirizine

CAS Registry Number

Drug Class

Breast Feeding

Lactation

Antihistamines


istrative Information

LactMed Record Number

62

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment.

You should consult your healthcare provider for breastfeeding advice related to your specific situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.


Cetirizine Levels and Effects while Breastfeeding

Summary of Use during Lactation

Small occasional doses of cetirizine are probably acceptable during breastfeeding.

What allergy medicine is safe to take while breastfeeding

Larger doses or more prolonged use may cause drowsiness and other effects in the baby or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established. The British Society for Allergy and Clinical Immunology recommends cetirizine at its lowest dose as a preferred choice if an antihistamine is required during breastfeeding.[1] Cetirizine has been used successfully in cases of persistent pain of the breast during breastfeeding.[2]

Ophthalmic use of cetirizine by the mom should pose little risk to the breastfed baby. To substantially decrease the quantity of drug that reaches the breastmilk after using eye drops, put pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

Effects in Breastfed Infants

In one telephone follow-up study, mothers reported irritability and colicky symptoms 10% of infants exposed to various antihistamines and drowsiness was reported in % of infants. None of the reactions required medical attention.[3]

A lady who was nursing (extent not stated) her newborn baby was treated for pemphigus with oral prednisolone 25 mg daily, with the dosage increased over 2 weeks to 60 mg daily.

She was also taking cetirizine 10 mg daily and topical betamethasone % twice daily to the lesions.

What allergy medicine is safe to take while breastfeeding

Because of a poor response, the betamethasone was changed to clobetasol propionate ointment %. She continued breastfeeding throughout treatment and her baby was developing normally at 8 weeks of age and beyond.[4]

A lady with narcolepsy took sodium oxybate 4 grams each night at 10 pm and 2 am as well as fluoxetine 20 mg and cetirizine 5 mg daily throughout pregnancy and postpartum. She breastfed her baby except for 4 hours after the 10 pm oxybate dose and 4 hours after the 2 am dose. She either pumped breastmilk or breastfed her baby just before each dose of oxybate.

The baby was exclusively breastfed or breastmilk fed for 6 months when solids were introduced. The baby was evaluated at 2, 4 and 6 months with the Ages and Stages Questionnaires, which were withing the normal range as were the infant’s growth and pediatrician’s clinical impressions regarding the infant’s growth and development.[5]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Antihistamines in relatively high doses given by injection can decrease basal serum prolactin in nonlactating women and in early postpartum women.[6][7] However, suckling-induced prolactin secretion is not affected by antihistamine pretreatment of postpartum mothers.[6] Whether lower oral doses of cetirizine own the same effect on serum prolactin or whether the effects on prolactin own any consequences on breastfeeding success own not been studied.

What allergy medicine is safe to take while breastfeeding

The prolactin level in a mom with established lactation may not affect her ability to breastfeed.

Alternate Drugs to Consider

Desloratadine, Fexofenadine, Loratadine

References

1. Powell RJ, Du Toit GL, Siddique N et al. BSACI guidelines for the management of chronic urticaria and angio-oedema. Clin Exp Allergy. ; PMID:

2. Muddana A, Asbill DT, Jerath MR et al.

What allergy medicine is safe to take while breastfeeding

Quantitative sensory testing, antihistamines, and beta-blockers for management of persistent breast pain: A case series. Breastfeed Med. ; PMID:

3.

What allergy medicine is safe to take while breastfeeding

Ito S, Blajchman A, Stephenson M et al. Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication. Am J Obstet Gynecol. ; PMID:

4. Westermann L, Hugel R, Meier M et al. Glucocorticosteroid-resistant pemphigoid gestationis: successful treatment with adjuvant immunoadsorption. J Dermatol. ; PMID:

5. Gashlin LZ, Sullo D, Lawrence RA et al. Treatment of narcolepsy with sodium oxybate while breastfeeding: A case report. Breastfeed Med. ; PMID:

6. Messinis IE, Souvatzoglou A, Fais N et al. Histamine H1 receptor participation in the control of prolactin secretion in postpartum.

J Endocrinol Invest. ; PMID:

7. Pontiroli AE, De Castro e Silva E, Mazzoleni F et al.

What allergy medicine is safe to take while breastfeeding

The effect of histamine and H1 and H2 receptors on prolactin and luteinizing hormone release in humans: sex differences and the role of stress. J Clin Endocrinol Metab. ; PMID:


Further information

Always consult your healthcare provider to ensure the information displayed on this sheet applies to your personal circumstances.

Medical Disclaimer


More about cetirizine ophthalmic

Related treatment guides

How does this medication work? What will it do for me?

This combination product contains two medications: senna and docusate sodium.

Senna belongs to the class of medications called stimulant laxatives.

What allergy medicine is safe to take while breastfeeding

Docusate sodium belongs to the family of medications known as stool softeners. Senna works by increasing the muscle activity in the digestive system, causing waste material to be eliminated as stool. Docusate sodium works by increasing the quantity of water in the stool, making stools softer and easier to pass.

This combination medication is used to treat occasional constipation due to hard stools. Specifically, it is recommended for women who own recently given birth; people for whom hard, dry stools should be avoided (e.g., people with hemorrhoids or anal fissures); and people for whom stool straining should be avoided (e.g., people with heart disease).

This combination generally produces a stool between 6 and 12 hours after taking the medication.

This medication may be available under multiple brand names and/or in several diverse forms. Any specific brand name of this medication may not be available in every of the forms or approved for every of the conditions discussed here. As well, some forms of this medication may not be used for every of the conditions discussed here.

Your doctor may own suggested this medication for conditions other than those listed in these drug information articles. If you own not discussed this with your doctor or are not certain why you are taking this medication, speak to your doctor.

Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they own the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.


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