Penicillin allergy what antibiotics to avoid
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take additional medicine to make up the missed dose.
Do not use this medication if you are allergic to penicillin V or to any other penicillin antibiotic, such as amoxicillin (Amoxil), ampicillin (Omnipen, Principen), carbenicillin (Geocillin), dicloxacillin (Dycill, Dynapen), or oxacillin (Bactocill).
Before using penicillin V, tell your doctor if you are allergic to cephalosporins such as Ceclor, Ceftin, Duricef, Keflex, and others, or if you own asthma, kidney disease, a bleeding or blood clotting disorder, a history of diarrhea caused by taking antibiotics, or a history of any type of allergy.
Penicillin V can make birth control pills less effective, which may result in pregnancy.
Before taking this medicine, tell your doctor if you use birth control pills. Take penicillin V for the entire length of time prescribed by your doctor.
Your symptoms may get better before the infection is completely treated. Penicillin V will not treat a viral infection such as the common freezing or flu.
Do not give this medication to another person, even if they own the same symptoms you do.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you own diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
Before taking this medicine
Do not use this medication if you are allergic to penicillin V or to any other penicillin antibiotic, such as:
dicloxacillin (Dycill, Dynapen); or
ampicillin (Omnipen, Principen);
amoxicillin (Amoxil, Amoxicot, Biomox, Dispermox, Trimox);
Before using penicillin V, tell your doctor if you are allergic to any drugs (especially cephalosporins such as Ceclor, Ceftin, Duricef, Keflex, and others), or if you have:
a history of diarrhea caused by taking antibiotics; or
a bleeding or blood clotting disorder;
a history of any type of allergy.
If you own any of these conditions, you may need a dose adjustment or special tests to safely take penicillin V.
FDA pregnancy category B.
Penicillin V is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Penicillin V can make birth control pills less effective, which may result in pregnancy. Before taking this medicine, tell your doctor if you use birth control pills. Penicillin V can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take penicillin?
Take penicillin V exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.
Follow the directions on your prescription label.
You may take penicillin V with or without food.
To be certain penicillin V is helping your condition, your blood may need to be tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.
Shake the oral suspension (liquid) well just before you measure a dose. To be certain you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon.
If you do not own a dose-measuring device, enquire your pharmacist for one.
Take penicillin V for the entire length of time prescribed by your doctor.
Your symptoms may get better before the infection is completely treated. Penicillin V will not treat a viral infection such as the common freezing or flu. Do not give this medicine to another person, even if they own the same symptoms you do.
Penicillin V can cause you to own unusual results with certain medical tests. Tell any doctor who treats you that you are using penicillin V.
Store penicillin V tablets at room temperature away from moisture, heat, and light. Store liquid penicillin V in a refrigerator but do not permit it to freeze.
Throw away any liquid that has not been used within 14 days after it was mixed at the pharmacy.
What is penicillin?
Penicillin V is an antibiotic in the penicillin group of drugs. It fights bacteria in your body.
Penicillin V is used to treat numerous diverse types of infections caused by bacteria, such as ear infections,.
Penicillin V may also be used for other purposes not listed in this medication guide.
The findings outline the need for healthcare staff to check that only bona fide penicillin allergies are recorded, in line with NICE recommendations on suspected allergy to Beta‑lactam antibiotics, which form part of NICE guideline ‘Drug allergy: diagnosis and management’.
The paper also highlights how antibiotics prescribing should be done responsibly in order to avoid the spread of antimicrobial resistance, in line with the NICE guideline on antimicrobial stewardship.
NICE is producing a range of antimicrobial prescribing guidelines to assist prescribers to select the most suitable antibiotics for specific conditions.
Prof Gillian Leng, deputy chief executive of NICE said: “Lots of people ponder they are allergic to penicillin because it gave them a rash when they were a kid, their mum or dad told them they were allergic and it has stayed in their notes for decades. That is a extremely diverse thing to having a true penicillin allergy, which can result in a life-threatening anaphylactic reaction.
“If healthcare staff use NICE guidance to distinguish properly between the two, that could assist stop the spread of both MRSA and antimicrobial resistance.”
For more MECs from NICE, sign up to the medicines awareness service email.
“We used to tell nine out of 10 people who report a penicillin allergy are skin-test negative.
Now it looks more love 19 out of 20,” said Dr. David Lang, president-elect of the American Academy of Allergy, Asthma and Immunology and chairman of allergy and immunology in the respiratory institute at the Cleveland Clinic.
Patients can get mislabeled as allergic to penicillin in a number of diverse ways. They may experience bad drug reactions love headaches, nausea or diarrhea, which are not true allergic reactions but are misinterpreted.
Alternatively, they may develop a symptom love a rash, which is indicative of a genuine allergic reaction but could be caused by an underlying illness and not by the drug.
And numerous people who own avoided penicillin for a decade or more after a true, severe allergic reaction will not experience that reaction again. “Even for those with true allergy, it can wane,” said Dr. Kimberly Blumenthal, the review’s senior author, who is an allergist and an assistant professor at Harvard Medical School. “We don’t really understand this, but once you’ve proven you’re tolerant, you go back to having the same risk as someone who never had an allergy” to penicillin.
It’s a excellent thought to discover out if your allergy is genuine or not because penicillin antibiotics, which are part of a group of drugs called beta-lactam antibiotics, are among the safest and most effective treatments for numerous infections.
Beta-lactams are the treatment of choice for Group A Streptococcus, which can cause pneumonia, toxic shock and other syndromes; Group B Strep, which causes meningitis; Staphylococcus aureus and other pathogens. Beta-lactams are used prophylactically to prevent infections during surgery, and studies own found that patients with penicillin allergies who are given second-line antibiotics before surgery had a substantially greater risk of a surgical site infection.
Beta-lactams are also the first line treatment for syphilis and gonorrhea.
Substitutes love fluoroquinolones, clindamycin, vancomycin and third-generation cephalosporins are available, but they are often both less effective and more expensive, and numerous are broader spectrum antibiotics, which can lead to the development of resistant organisms and other side effects, experts tell. Studies own shown that patients with penicillin allergies are at increased risk for developing serious infections love Clostridium difficile, methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant enterococcus.
Don’t challenge yourself to penicillin on your own, experts warn.
Patients who own been told they’re allergic to penicillin should talk to their doctors, who should take a careful history and review the symptoms of the reaction.
If the past reaction to penicillin included symptoms love headache, nausea, vomiting and itching, or the diagnosis was made based on a family history of the allergy, the patient is considered low risk and may be capable to take a first dose of penicillin or a related antibiotic, such as amoxicillin, under medical observation.
If the past reaction included hives, a rash, swelling or shortness of breath, patients should own penicillin skin testing, which involves a skin prick test using a little quantity of penicillin reagent, followed by a second test that places the reagent under the skin if the first test is negative.
If both tests are negative, the patient is unlikely to be allergic to penicillin, and an oral dose may be given under observation to confirm.
The quantity of phenoxymethylpenicillin you need depends on your age and how bad the infection is, and whether you’re taking it to treat or prevent an infection.
What if I forget to take it?
If you forget to take a dose, take it as soon as you remember, unless it’s almost time for your next dose.
In this case, just leave out the missed dose and take your next dose as normal.
Never take 2 doses at the same time.
Never take an additional dose to make up for a forgotten one.
If you forget doses often, it may assist to set an alarm to remind you. You could also enquire your pharmacist for advice on other ways to remember your medicines.
How to take it
Swallow phenoxymethylpenicillin tablets whole. Do not chew or break them.
The medicine also comes as a liquid for people who discover it hard to swallow tablets.
If you or your kid are taking phenoxymethylpenicillin as a liquid, it’ll generally be made up for you by your pharmacist.
The medicine will come with a plastic syringe or spoon to assist you measure out the correct dose.
If you don’t own one, enquire your pharmacist for one. Do not use a kitchen teaspoon as it will not give the correct amount.
When to take it
Try to space the doses evenly throughout the day. If you take phenoxymethylpenicillin 4 times a day, this could be first thing in the morning, around midday, tardy afternoon and at bedtime.
If you’re taking it twice a day, leave 12 hours between each dose. This could be early morning and early evening, at 8am and 8pm.
It’s best not to take phenoxymethylpenicillin at mealtimes. Take it 30 minutes before a meal or at least 2 hours after you own eaten.
How much will I take?
For adults and children over 12 years, you’ll generally take:
- 500mg 4 times a day — for treating infections
- 500mg twice a day — for preventing infections
What if I take too much?
Accidentally taking an additional dose of phenoxymethylpenicillin is unlikely to harm you or your child.
Speak to your pharmacist or doctor if you’re worried, or if you take more than 1 additional dose.
Generic Name: penicillin V (pen i SILL in)
Brand Names:PC Pen VK, Pen-V
Medically reviewed by Sanjai Sinha, MD Final updated on Dec 22, 2018.
Higher MRSA rate
The study highlights previous evidence that around 10% of the UK population has a penicillin allergy documented in their clinical notes, but that only around 5% of these people actually own a ‘true’ penicillin allergy.
The study measured the rates of MRSA and C difficile in people who are, correctly or not, documented as having a penicillin allergy.
Those people are almost 70% more likely to develop MRSA – the bacteria often referred to as a «hospital superbug».
They are also around 25% more likely to develop C difficile, a bacteria that generally causes diarrhoea, according to a 2018 study of almost 300,000 patient records.